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coli-expressed protein, this is a critical gap

doi: 10.1111/jam.12461 [DOI] [PubMed] [Google Scholar] 243

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These discrepancies may arise from differences in sample sizes, study designs, and the power of individual datasets to detect genetic associations

Owing to these actions, the principal sites of POMC expression and its processing into biologically active -MSH lie within the central nervous system (hypothalamus and pituitary gland) and in the skin, but there is some evidence demonstrating that -MSH is also produced in other peripheral tissues (Smith and Funder, 1988)